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Regenexx® Stem Cell Procedures for Shoulder Arthritis, Rotator Cuff Tears & Other Shoulder Conditions.

The Regenexx® family of non-surgical stem-cell & blood platelet procedures are next generation regenerative injection treatments for those who are suffering from shoulder pain due to arthritis, rotator cuff and shoulder labrum tears, overuse injuries, and other degenerative conditions. Regenexx is also a viable alternative for those considering shoulder replacement surgery.

If you have encountered a rotator cuff tear, or experience pain related to shoulder arthritis, tendonitis, tendenosis, or bursitis, you may be a good candidate for a Regenexx Procedure. Shoulder surgery is particularly difficult due to the complexity of the joint. Post surgical recovery can be painful, requiring a lengthy rehab period to restore strength and mobility to the shoulder. As an alternative to shoulder surgery, Regenexx Procedures may help alleviate shoulder pain and restore joint damage with a non-invasive injection procedure. Patients typically experience little or no down time from the procedure.

View Shoulder Outcome Data

Commonly Treated Shoulder Conditions

This is not a complete list, so please contact us or complete the Regenexx Candidate Form if you have questions about whether you or your condition can be treated with these non-surgical procedures.

  • Rotator cuff tears
  • Arthritis of the shoulder joint
  • Thoracic outlet syndrome
  • Labral tears or degeneration
  • Rotator cuff tendonitis & tendonosis
  • AC Joint Separation
  • Recurrent shoulder dislocations

Your Alternative to Shoulder Surgery

The Regenexx Procedure for Rotator Cuff Tears is a patented same-day stem cell procedure.  Through years of research and perfecting the use of stem cells and platelets to repair rotator cuff tears, Regenexx improves the rotator cuff’s regenerative potential, rather than further damaging an area that has given way because of tissue weakness.

Video Overview – The Regenexx Procedure for Shoulder and Rotator Cuff

Using a precise, image-guided injection of your own stem cells and growth factors, we are able to get more of the body’s natural “repairmen” directly into the tear.  By mobilizing your body’s own healing mechanisms and eliminating the trauma of surgery and atrophy caused by immobilization, Regenexx has produced good results in the treatment of partial rotator cuff tears and has even shown encouraging success with completely retracted tears.


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Find out if you are a Regenexx candidate

How Stem Cell Therapy & Platelet-Rich Plasma Works

Stem Cell Treatments

Stem cells exist in every part of the human body. Their job is to repair damage, such as broken bones, paper cuts, sports injuries, torn ligaments, muscle tears, and more. The human body contains a finite number of stem cells, which means an injured area of the body cannot get enough of the stem cells it needs to heal properly. Regenexx Procedures solve that problem by delivering a high concentration of stem cells directly to the injured area.

Stem cell therapy works quickly, which allows patients to avoid the long, painful rehabilitation periods normally associated with surgery or other approaches. Furthermore, there is very little downtime associated with stem cell therapy, so patients can get back to their normal lives right away.

Adult stem cells are different from other cells in your body in that they can differentiate, or turn into other cells. They live in various tissues around the body, ideally located to quickly repair damage as soon as it happens. We may not always have enough stem cells in a given area to repair damage quickly, though, which can lead to a slow or incomplete recovery. Those who sustain a large injury may not have enough stem cells in the area of the injury to respond adequately, for example, and the number of available stem cells can decrease as we age.

Utilizing a personalized lab prep method, we concentrate your own bone marrow into a high concentration of stem cells and growth factors. Then utilizing the highest level of imaging guidance, your cells are then injected into the tissue that is damaged and requires treatment.

The highly trained physicians at Chicago Arthritis and Regenerative Medicine use the patented Regenexx Stem Cell Procedures for a wide variety of conditions. Proven safe and effective, our stem cell procedures have become the treatment of choice when it comes to treating arthritis, tendinitis, injuries, and back pain. 

Blood Platelet Treatments

Your blood contains healing growth components that give your body the ability to repair itself naturally by stimulating the stem cells in the targeted area. These healing growth components make stem cells work harder to heal damaged tissue.

Platelet Rich Plasma (PRP) and Platelet Lysate Injection Treatments use the healing growth components found in your own body to accelerate the healing of injured muscles, ligaments, tendons, and joints.

Platelets are small fragments of cells, stocked with compounds that initiate clotting to stop bleeding and growth factors that trigger healing.

These growth factors are specialized chemicals that communicate with other cells, organize the cells for healing, and energize the healing effort. Blood platelet therapy with PRP simply concentrates the platelets in a sample of plasma, which is the watery part of the blood.

We create a personalized platelet product by taking a blood draw from you, concentrating in our lab, and creating a platelet product specific for your condition. 

The concentrated platelets known as Platelet Rich Plasma (PRP) slowly release growth factor over the course of a few days. Platelet Lysate is similar to PRP, except that it adds a step in the procedure that breaks open the platelets to make the growth factor more readily accessible to the affected tissue.

The Regenexx Difference

As the most advanced orthopedic stem cell protocol in the world, Regenexx is 100% focused on orthopedic conditions & producing the best possible outcomes.

20× More Stem Cells

Regenexx procedures contain up to 20 times more stem cells than standard stem cell procedures.


Regenexx prides itself as the most researched stem cell protocol for orthopedic conditions.

Image-Guided Injections

Regenexx physicians utilize image-guided cell injections & harvesting for absolute precision.

Superior Source

Unlike other stem cell clinics, Regenexx uses bone marrow derived stem cells, which outperform fat derived cells.


Regenexx is a complete stem cell protocol—not a single procedure.

Transparent Data

Annually published patient outcomes and safety data.

Shoulder 2.0

How You Can Avoid Invasive Shoulder Surgery

Written by regenerative medicine expert, Chris Centeno, M.D., Shoulder 2.0 delves deep into the workings and complexity of the shoulder. He shares the details of how the world of shoulder surgery will be upended by a new medical specialty called Interventional Orthopedics. This book focuses on each part of the shoulder, complex as it is interconnected to the whole, and on the shift of surgical salvage to the interventional orthopedic approach of shoulder repair.

Using the Regenexx SANS approach, Shoulder 2.0 walks you through a series of tests you can do on your own to better understand where your body is struggling to maintain proper alignment and stability, explaining the possible reasons and long term implications along the way. Shoulder 2.0 explores how Regenexx is further advancing the field of Interventional Orthopedics they helped to invent, where the uses of regenerative orthobiologics such as bone marrow concentrate source of stem cells and platelet rich plasma are used to help the body repair and strengthen damaged tissues, opposed to invasive surgeries that often remove important tissues of the shoulder.

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